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HEMOSTASIS
- von Willebrand Factor Antigen ELISA
- von Willebrand Factor Activity ELISA
- Protein C Antigen ELISA
- Protein S Antigen (total & free) ELISA
Price: 345 Euro/ kit
von Willebrand Factor (VWF) is a pro-coagulant
protein which plays an important role in hemostasis. von Willebrand disease,
(vWD), the most common inherited bleeding disorder, is caused by either
quantitative (Type I) or qualitative (Type II) deficiency. Both quantitative
(antigenic) and qualitative (functional) assays are important in the
diagnosis and treatment of vWD.
- von Willebrand Factor Antigen ELISA is a quantitative test
for determining von Willebrand Factor Antigen levels in citrated human
plasma.
- von Willebrand Factor Activity Test is an ELISA for detecting
VWF activity in citrated human plasma. A purified monoclonal antibody
which recognizes a functional epitope on the vWF antigen is used to
measure vWF activity (function), rather than total vWF concentration.
Protein C contributes to the maintenance of
normal hemostasis by limiting clot formation and promoting fibrinolysis.
Deficiency, either congenital or acquired, may lead to serious thrombotic
events.
Protein S serves as a cofactor for the
anticoagulant and fibrinolytic effects of activated protein C. Protein S
deficiency, either congenital or acquired, may lead to serious thrombotic
events. The measurement of both total and free Protein S (the functionally
active form) is useful in classifying patients with congenital Protein S
deficiency. |
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Last modified:
05/19/16
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