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HEMOSTASIS
  • von Willebrand Factor Antigen ELISA
  • von Willebrand Factor Activity ELISA
  • Protein C Antigen ELISA
  • Protein S Antigen (total & free) ELISA

  Price: 345 Euro/ kit

von Willebrand Factor (VWF) is a pro-coagulant protein which plays an important role in hemostasis. von Willebrand disease, (vWD), the most common inherited bleeding disorder, is caused by either quantitative (Type I) or qualitative (Type II) deficiency. Both quantitative (antigenic) and qualitative (functional) assays are important in the diagnosis and treatment of vWD.

  • von Willebrand Factor Antigen ELISA is a quantitative test for determining von Willebrand Factor Antigen levels in citrated human plasma.
  • von Willebrand Factor Activity Test is an ELISA for detecting VWF activity in citrated human plasma. A purified monoclonal antibody which recognizes a functional epitope on the vWF antigen is used to measure vWF activity (function), rather than total vWF concentration.

Protein C contributes to the maintenance of normal hemostasis by limiting clot formation and promoting fibrinolysis. Deficiency, either congenital or acquired, may lead to serious thrombotic events.

Protein S serves as a cofactor for the anticoagulant and fibrinolytic effects of activated protein C. Protein S deficiency, either congenital or acquired, may lead to serious thrombotic events. The measurement of both total and free Protein S (the functionally active form) is useful in classifying patients with congenital Protein S deficiency.


 

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Last modified: 05/19/16