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Anti-Rattin (Humanin-like) Polyclonal Antibody

  Catalog Number:         25-24359                                                                                   Price: 333 Euro

 Lot Number:                R5731

 Quantity:                     100 mg in 100 ml (1 mg/ml) in PBS containing 0.02% sodium azide. 

Description:                 A novel rat gene, Rattin, encodes a peptide homologous to Humanin, a secreted peptide that specifically protects against neuronal cell death induced by beta-amyloid peptide (Ab) or by mutations causing early-onset familial Alzheimer's disease. Rattin is the prototype of a novel class of peptides, phylogenetically related to Humanin, endowed with protective activity not only against Ab but also toward excitotoxic neuronal death. The rat gene, Rattin, encodes a peptide of 38 residues (15 residues longer than Humanin) showing 73% identity in the conserved region to Humanin.

 Host Species:              Rabbit

Specificity:                   Reacts with residues 20-35 [VKRLESPNKTRRPYGA] of the Rattin peptide, which is not in the conserved region to Humanin.

 Applications:                Western blot – Use at 1:500 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

 Format:                       Affinity purified IgG  

Storage:                       Maintain at +2-8°C for 3 months or at -20°C for longer periods.  Stable for 1 year. Avoid repeated freeze-thaw cycles.

 Reference:      Caricasole A. et al. FASEB J. 2002 Aug;16(10):1331-3.

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Last modified: 05/19/16