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Interleukin 2 (IL-2)

 

 

l        Description

Recombinant human interleukin-2 is a sterile protein product for injection. rHuIL-2 is produced by recombinant DNA technology by Yeast. It is a highly purified protein containing 133 amino acids, with cysteine mutated to alanine at 125 amino acid position, and has a molecular weight of approximately 15.4kD, non-glycosylated.

 

l        Indication

1.      Indicated for the treatment of adults with metastatic renal cell carcinoma (metastatic RCC).

2.      Indicated for the treatment of adults with metastatic melanoma.

 

l        Pharmaceutical particulars

Sterile, clear, colorless and preservative-free liquid for injection in vial.

Dosage: 3 million IU (0.3ml)/vial

Reference: Current Chinese Pharmacopoeia and Internal requirement

Specific activity: ≥3×107IU/mg

Purity (HPLC, SDS-PAGE): ≥98%

 

l        Composition

Active ingredient: Recombinant Human Interleukin 2 (rHuIL-2)

Inactive ingredients: Glacial Acetic Acid, Mannitol, Polysorbate-80 and Sodium Acetate.

 

l        Shelf life and storage conditions

 

 Finished formulation

 Store at 2-8 for 2 years
 API (Concentrated solution)  Store at -70 for 12 months
 

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Last modified: 05/19/16