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Interferon gamma (IFN g)

 

 

l        Description

Recombinant Human Interferon gamma-1b is a sterile protein product for injection. rHuIFN g is produced by recombinant DNA technology by E.coli carrying a genetically engineered plasmid containing human interferon gamma gene. It is a highly purified protein containing 140 amino acids, and has a molecular weight of approximately16.5kD.

 

l        Indication

1.      Indicated for reducing the frequency and severity of serious infections associated with Chronic Granulomatous Disease.

2.      Indicated for delaying time to disease progression in patients with severe, malignant osteopetrosis.

 

 

l        Pharmaceutical particulars

Sterile, clear, colorless and preservative-free liquid for injection in vials.

Dosage: 1 million IU (0.5ml)/vial

Reference: current Chinese Pharmacopoeia and Internal Requirement

Specific activity: 2.0×107 IU/mg

Purity (HPLC, SDS-PAGE): ≥98%

 

 

l        Composition

Active ingredient: Recombinant Human Interferon gamma (IFN gamma)

Inactive ingredients: Succinic acid, Mannitol and Polysorbate-20

 

l        Shelf life and storage conditions

 

 Finished formulation  Store at 2-8 for 2 years
 API (Concentrated solution)  Store at -70 for 12 months
 

 

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Last modified: 05/19/16