Interferon alfa-2a (IFN a-2a)

 

 

l        Description

Recombinant Human Interferon alfa-2a is a sterile protein product for injection. rHuIFN a-2a is produced by recombinant DNA technology by Yeast carrying a genetically engineered plasmid containing human interferon alfa-2a gene. It is a highly purified protein containing 165 amino acids, and has a molecular weight of approximately 19.2kD.

 

l        Indication

1.      Treatment of chronic hepatic C

2.      Treatment of hairy cell leukemia

3.      AIDS-related Kaposi’s sarcoma

4.      Indicated for chronic phase, Philadelphia chromosome(Ph) positive chronic myelogenous leukemia (CML)

 

 

l        Pharmaceutical particulars

Sterile, clear, colorless and preservative-free liquid for injection in vial.

Dosage: 3 million IU (0.3ml)/vial

Reference: Current European Pharmacopoeia and Internal Requirement

Specific activity: ≥2.0×10⁸ IU/mg
Purity (HPLC, SDS-PAGE): ≥98%

 

 

l        Composition

Active ingredient: Recombinant Human Interferon alfa-2a (rHuIFN a-2a)

Inactive ingredients: Sodium chloride, Polysobate-80, Glacial acetic acid, Sodium acetate.

 

l        Shelf life and storage conditions

 

Finished formulation	Store at 2-8℃ for 2 years
API (Concentrated solution)	Store at -70℃ for 12 months