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Breast
Cancer Resistant Protein
Clone: BXP-34
Breast cancer resistance protein is an
ATP-Binding Cassette half-transporter. BCRP may be over-expressed in
cancer cell lines selected with doxorubicin/verapamil, topotecan or
mitoxantrone. Signet clone BXP-34 reacts with an internal epitope of
BCRP (70kD) membrane transport protein involved in multidrug resistance
(MDR). Clone BXP-34 does not cross react with the human MDR1, MRP1,
MRP2, MRP5 gene products. Clone BXP-34 may be used to detect BCRP
mediated drug resistance in tumor samples. The immunogen is BCRP
over-expressing cell line MCF 7 MR. Known applications are ICC and IHC
(frozen). This antibody is not reactive in Western blotting.
Master Cat. No. 8820 Cat. No. 8820-01
Clone: BXP-34 |
Catalog # |
Format |
Quantity |
Price |
8820-01 |
Concentrate |
1ml |
463.50 |
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Last modified:
05/19/16
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