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Breast Cancer Resistant Protein
Clone: BXP-34

Breast cancer resistance protein is an ATP-Binding Cassette half-transporter. BCRP may be over-expressed in cancer cell lines selected with doxorubicin/verapamil, topotecan or mitoxantrone. Signet clone BXP-34 reacts with an internal epitope of BCRP (70kD) membrane transport protein involved in multidrug resistance (MDR). Clone BXP-34 does not cross react with the human MDR1, MRP1, MRP2, MRP5 gene products. Clone BXP-34 may be used to detect BCRP mediated drug resistance in tumor samples. The immunogen is BCRP over-expressing cell line MCF 7 MR. Known applications are ICC and IHC (frozen). This antibody is not reactive in Western blotting.
Master Cat. No. 8820 Cat. No. 8820-01 Clone: BXP-34

Catalog # Format Quantity Price
8820-01   Concentrate   1ml   463.50  

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